Methodological developments

Exact estimation methods in nonlinear mixed-effect models
Design optimisation in nonlinear mixed-effect models
Model evaluation in nonlinear mixed-effect models
Model selection, covariate tests and pharmacogenetics
Modelling data from interaction or bioequivalence studies

Applications

Pharmacology and pharmacogenetics of antiretroviral drugs in HIV patients
Variability of the response to oral anticoagulant drugs
Pharmacokinetic/pharmacodynamic parameters, efficacy and antibiotic resistance
Chemosensitivity to antimalarial agents
Evolution of biomarkers of the Gaucher disease, with or without treatment
Infectious endocarditis
Pharmacogenetics of anti-TNF drugs
Bioequivalence of monoclonal antibodies