Our selected publications (Last update : 21/08/09 )

1. Retout S, Comets E, Samson A, Mentré F.
   Design in nonlinear mixed effects models: optimization using the Fedorov-Wynn algorithm and power of the Wald test for binary covariates.
   Statistics in Medicine, 2007, 26, 5162- 5179. (Link to full text)
   
   
2. Panhard X, Taburet AM, Piketti C, Mentré F.
   Impact of modelling intra-subject variability on tests based on non-linear mixed-effects models in crossover PK trials with application to the interaction of tenofovir on atazanavir in HIV patients.
   Statistics in Medicine, 2007, 26, 1268-1284. (Link to full text)
   
3. Samson A, Lavielle M, Mentré F.
   Extension of the SAEM algorithm to left-censored data in nonlinear mixed-effects model: Application to HIV dynamics model.
   Computational Statistics and Data Analysis, 2006, 51, 1562-1574. (Link to full text)
   
   
4. Brendel K, Comets E, Laffont C, Laveille C, Mentré F.
   Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide
   Pharmaceutical Research, 2006, 23, 2036-2049. (Link to full text)
   
   
5. Bazzoli C, Retout S, Mentré F.
   Fisher information matrix for nonlinear mixed effects multiple response models: Evaluation of the appropriateness of the first order linearization using a pharmacokinetic/pharmacodynamic model.
   Statistics in Medicine, 2009.
   Link to publication
   
   
6. Gros PA*, Le Nagard H*, Tenaillon O
   The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation.
   Genetics, 2009, 182, 277–293.
   * The two authors equally contributed to this work
   Link to publication
   
   
7. Panhard X, Samson A.
   Extension of the SAEM algorithm for nonlinear mixed models with 2 levels of random effects.
   Biostatistics, 2009, 10, 121-135.
   Link to publication
   
   
8. Bertrand J, Comets E, Mentré F.  
   Comparison of model-based tests and selection strategies to detect genetic polymorphisms influencing pharmacokinetic parameters. 
   Journal of Biopharmaceutical Statistics , 2008, 18, 1084-1102.
   Link to publication
   
   
9. Duval X, Leport C.
   Prophylaxis of infective endocarditis: current tendencies, continuing controversies.
   The Lancet Infectious Diseases, 2008, 8, 225-232.